The major circulating form of vitamin D is 25-hydroxyvitamin D (25(OH)D); thus, the total serum 25(OH)D level is currently considered the best indicator of vitamin D supply What to expect. The 25-hydroxy vitamin D test involves providing a blood sample. To take a blood sample, a healthcare provider will first clean the skin on the person's arm. Then they will draw Wskaźnikiem zaopatrzenia organizmu w witaminę D jest stężenie 25-hydroksywitaminy D w surowicy (25-OHD). W badaniu oznacza się nieaktywną biologicznie formę witaminy D, ponieważ poziom 1,25-(OH)2 D może być w normie nawet przy niedoborach witaminy w organizmie. Ile wynosi norma witaminy D3? 25-OH Vitamin D Calcidiol D2 D3 Vitamin D Assay 25HDN 25OHD 25DEP Calciferol Ergocalciferol Cholecalciferol Colecalciferol CYP2R1 Diagnosis of vitamin D deficiency Differential diagnosis of causes of rickets and osteomalacia Monitoring vitamin D replacement therapy Diagnosis of hypervitaminosis D An intake of no less than 1000 IU (25 mcg) of vitamin D3 (cholecalciferol) per day for all adults may bring at least 50% of the population up to 75 nmol/l. Thus, higher doses of vitamin D are needed to bring most individuals into the desired range. At that time, their experts concluded: "Based on all the evidence, at a minimum, we recommend vitamin D levels of 30 ng/mL, and because of the vagaries of some of the assays, to guarantee sufficiency, we recommend between 40 and 60 ng/mL for both children and adults." Based on this evidence, the committee concluded that the bone-strengthening benefits of vitamin D plateau when blood levels (as measured by a standard vitamin D blood test) reach 12 to 16 Reference ranges for 1,25 (OH) 2 D may be reported as either pg/mL or pmol/L. The molecular weight of 1,25 (OH) 2 D is approximately 416.7, yielding the following conversion factors: 1 Normal Results. The normal range of 25-hydroxy vitamin D is measured as nanograms per milliliter (ng/mL). Many experts recommend a level between 20 and 40 ng/mL. Others recommend a level between 30 and 50 ng/mL. The examples above are common measurements for results of these tests. Główną postacią, pod którą witamina D występuje w krążeniu, jest 25-hydroksywitamina D (inaczej 25(OH)D, 25-hydroksycholekalcyferol, kalcydiol), czyli metabolit będący efektem pierwszej hydroksylacji cząsteczki witaminy D2 i D3 w pozycji 25, do której dochodzi w wątrobie. Normal Results. The normal range of 25-hydroxy vitamin D is measured as nanograms per milliliter (ng/mL). Many experts recommend a level between 20 and 40 ng/mL. Others recommend a level between 30 and 50 ng/mL. The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. According to the Endocrine Society, vitamin D deficient adults should be treated with 50,000 IU (1250 ug) of vitamin D weekly [equal to 7143 IU (179 ug) daily] for eight weeks to achieve a blood level greater than 30 ng/mL (75 nmol/L). Maintenance therapy thereafter should be at least 1500-2000 IU (38-50 ug) per day. The consensus is that levels of 25(OH)D below 25nmol/L indicate 'deficiency'. Some have argued that this level is conservative. Raising the definition of "deficiency" or "sufficiency" to higher levels is inappropriate until results from randomised trials can show that maintaining such levels has clear health benefits and no health risks. Vitamin D tests, which include immunoassays and liquid chromatography-mass spectrometry LC/MS/MS, measure the level of 25(OH)D, the main form of circulating vitamin D. Optimal levels Vitamin D levels of 30 to 100 ng/mL are considered optimal. The Endocrine Society, the National and International Osteoporosis Foundation, and the American Geriatric Society define vitamin D deficiency as the level of 25-hydroxyvitamin (25 OH D) of less than 30 ng/mL. The Endocrine Society recommends a preferred range of 40 to 60 ng/mL. .
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